HPLC columns

stabel in 100 % aqueous eluent systems- USP L1
pore size 110 Å, particle sizes 1,8µm, 3µm and 5µm; 14 % C
7 and 10µm particles for preparative separations on request
interesting polar selectivity features
excellent base deactivation; suitable for LC/MS due low bleeding characteristics
pH stability 1 - 9
Ideal for: analgesics, penicillin antibiotics, nucleic acid bases, water-soluble vitamins, complexing agetns, organic acids
particle size 5µm, 14% C

NUCLEODUR^® C18 - C 8 Gravity nonpolar high density phases

available as octadecyl (C18 -USP L!) and octyl (C8 - USP L7) modifications
Pore size 110 Å; particle sizes 1,8µm, 3µm and 5µm for C18, 1,8 and 5µm for C8
7, 10, 12 and 16µm particles for preparative separations on request
carbon content 18 %C for C18 , 11%C for C8
ideal for method development
allows HPLC at pH extremes (pH 1 - 11)
suitable for LC/MS due to low bleeding characteristics
recommended for overall sophisticated analytical separations
optimal for: pharmaceuticals, e.g. analgesics, antiinflammatory drugs, antidepressants; herbicides; phytopharmaceuticals; immunosppressants
particle size 5µm, 11% C

NUCLEODUR^® C18 - C 8 Gravity nonpolar high density phases

available as octadecyl (C18 -USP L!) and octyl (C8 - USP L7) modifications
Pore size 110 Å; particle sizes 1,8µm, 3µm and 5µm for C18, 1,8 and 5µm for C8
7, 10, 12 and 16µm particles for preparative separations on request
carbon content 18 %C for C18 , 11%C for C8
ideal for method development
allows HPLC at pH extremes (pH 1 - 11)
suitable for LC/MS due to low bleeding characteristics
recommended for overall sophisticated analytical separations
optimal for: pharmaceuticals, e.g. analgesics, antiinflammatory drugs, antidepressants; herbicides; phytopharmaceuticals; immunosppressants
particle size 5µm, 18% C

distinct selectivity based on bifunctional surface coverage - USP L1 and USP L11
pore size 110 Å, particle sizes 1,8µm, 3µm and 5µm; 14 %C
high density of covalently bonded silanes for tailing-free peaks widens the scope for method development
pH stability 1 - 10
suitable for LC/MS due low bleeding characteristics
high reproducibility and consistent quality due to tight QC procedures
range of application: quinolone antibiotics, sulfonamides, xanthines, substituted aromatics
particle size 3µm, 14% C

distinct selectivity based on bifunctional surface coverage - USP L1 and USP L11
pore size 110 Å, particle sizes 1,8µm, 3µm and 5µm; 14 %C
high density of covalently bonded silanes for tailing-free peaks widens the scope for method development
pH stability 1 - 10
suitable for LC/MS due low bleeding characteristics
high reproducibility and consistent quality due to tight QC procedures
range of application: quinolone antibiotics, sulfonamides, xanthines, substituted aromatics
particle size 5µm, 14% C

pore size 110 Å, particle sizes 3µm and 5µm; 7%C - USP L10
multi-mode columns (RP and NP)
widens the scope in selectivity
differnet retention characteristics compared to C8 and C18
stable against hydrolysis at low pH values, working range pH 1-8
high reproducibility from lot to lot
ideal for: tricyclic antidepressants, steroids, organic acids
eluent in column acetonitrile, particle size 3µm.

pore size 110 Å, particle sizes 3µm and 5µm; 7%C - USP L10
multi-mode columns (RP and NP)
widens the scope in selectivity
differnet retention characteristics compared to C8 and C18
stable against hydrolysis at low pH values, working range pH 1-8
high reproducibility from lot to lot
ideal for: tricyclic antidepressants, steroids, organic acids
Eluent in column n-heptane, particle size 5µm.

pore size 110 Å, particle sizes 3µm and 5µm; 7%C - USP L10
multi-mode columns (RP and NP)
widens the scope in selectivity
differnet retention characteristics compared to C8 and C18
stable against hydrolysis at low pH values, working range pH 1-8
high reproducibility from lot to lot
ideal for: tricyclic antidepressants, steroids, organic acids
eluent in column acetonitrile, particle size 5µm

pore size 110 Å, particle sizes 3 and 5µm; 2,5%C; not endcapped - USP L8
multi-mode columns (RP and NP)
normal phase chromatography (NP) with hexan, dichloromethane or 2-propanol as mobile phase for polar compounds such as substituted anilines, esters, chlorinated pesticides
reversed phase chromatography (RP) of polar compounds like sugars in aqueous-organic eluent systems
ion exchange chromatography of anions and organic acids using common buffers and organic modifiers
stable against hydrolysis at low pH, working range pH 2-8, 100% stable in water, suitable for LC-MS
Ideal for:
polar compounds under RP conditions (sugars, DNA bases), hydrocarbons under NP conditions
Eluent in column is n-heptane for the NP mode - RP columns are delivered in acetonitrile - water. For changing the solvent system a rinsing step with THF may be necessary.
eluent in column n-heptane, particle size 5µm.

pore size 110 Å, particle sizes 3 and 5µm; 2,5%C; not endcapped - USP L8
multi-mode columns (RP and NP)
normal phase chromatography (NP) with hexan, dichloromethane or 2-propanol as mobile phase for polar compounds such as substituted anilines, esters, chlorinated pesticides
reversed phase chromatography (RP) of polar compounds like sugars in aqueous-organic eluent systems
ion exchange chromatography of anions and organic acids using common buffers and organic modifiers
stable against hydrolysis at low pH, working range pH 2-8, 100% stable in water, suitable for LC-MS
Ideal for:
polar compounds under RP conditions (sugars, DNA bases), hydrocarbons under NP conditions
Eluent in column is n-heptane for the NP mode - RP columns are delivered in acetonitrile - water. For changing the solvent system a rinsing step with THF may be necessary.
eluent in column acetonitrile, particle size 5µm.